The results in overdosage will likely be potentiated by simultaneous ingestion of Liquor and psychotropic medicine.
Codeine can also be contraindicated in situations in which inhibition of peristalsis is always to be prevented, wherever There's a possibility of paralytic ileus, the place abdominal distension develops, or in acute diarrhoeal disorders like acute ulcerative colitis or antibiotic associated colitis (e.g. pseudomembranous colitis) or diarrhoea because of poisoning.
If Gals just take this drug throughout pregnancy, There exists a possibility that their newborn infants will experience neonatal withdrawal syndrome.
Both equally medications pose a chance of overdose and withdrawal, so it is vital to discuss dosage and tapering with a physician.
Codeine is also contraindicated in circumstances exactly where inhibition of peristalsis is usually to be avoided, exactly where You will find a hazard of paralytic ileus, where abdominal distension develops, or in acute diarrhoeal disorders like acute ulcerative colitis or antibiotic affiliated colitis (e.g. pseudomembranous colitis) or diarrhoea brought on by poisoning.
Be sure to verify Should you be a member of the general public, or possibly a patient prescribed a Teva medicine by a UK healthcare Skilled (or their caregiver) or if you are United kingdom healthcare Experienced.
Be sure to Stick to the directions carefully, due to the fact continuing constipation may result in more severe issues.
Drug withdrawal syndrome might take place on abrupt cessation of therapy or dose reduction. Every time a patient no longer calls for therapy, it really is recommended to taper the dose progressively to minimise indications of withdrawal. click here Tapering from a significant dose could choose weeks to months.
People today must retain opioids clear of children and may not choose them with certain other drugs, Primarily benzodiazepines.
Children with compromised respiratory perform Codeine is not encouraged for use in little ones in whom respiratory operate is likely to be compromised like neuromuscular Conditions, intense cardiac or respiratory situations, upper respiratory or click here lung infections, multiple trauma or comprehensive surgical strategies. These components could worsen indications of morphine toxicity.
Codeine may perhaps impair mental and/or physical skills demanded with the general performance of doubtless dangerous jobs such as driving a vehicle or operating machinery. This kind of jobs ought to be averted while having this solution.
Overuse or misuse could end in overdose and/or death. It is important that people only use medicines that happen to be prescribed for them with the dose they are prescribed and do not give this medication to anyone else.
Discontinuation must be completed steadily in people who could possibly have produced Bodily dependence, to avoid precipitating withdrawal signs and symptoms.
Antidepressants: The depressant results of opioid analgesics could be enhanced by tricyclic antidepressants.